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Structure, Properties, and Engineering of the Major Zinc Binding Site on Human Albumin
Most blood plasma zinc is bound to albumin, but the structure of the binding site has not been determined. Zn K-edge extended x-ray absorption fine structure spectroscopy and modeling studies show that the major Zn(2+) site on albumin is a 5-coordinate site with average Zn-O/N distances of 1.98 Å an...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755717/ https://ncbi.nlm.nih.gov/pubmed/19520864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003459 |
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