Structure, Properties, and Engineering of the Major Zinc Binding Site on Human Albumin

Most blood plasma zinc is bound to albumin, but the structure of the binding site has not been determined. Zn K-edge extended x-ray absorption fine structure spectroscopy and modeling studies show that the major Zn(2+) site on albumin is a 5-coordinate site with average Zn-O/N distances of 1.98 Å an...

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Hlavní autoři: Blindauer, Claudia A., Harvey, Ian, Bunyan, Kerry E., Stewart, Alan J., Sleep, Darrell, Harrison, David J., Berezenko, Stephen, Sadler, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755717/
https://ncbi.nlm.nih.gov/pubmed/19520864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003459
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