Architecture and Molecular Mechanism of PAN, the Archaeal Proteasome Regulatory ATPase

In Archaea, an hexameric ATPase complex termed PAN promotes proteins unfolding and translocation into the 20 S proteasome. PAN is highly homologous to the six ATPases of the eukaryotic 19 S proteasome regulatory complex. Thus, insight into the mechanism of PAN function may reveal a general mode of a...

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Bibliographic Details
Main Authors: Medalia, Noa, Beer, Avital, Zwickl, Peter, Mihalache, Oana, Beck, Martin, Medalia, Ohad, Navon, Ami
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755702/
https://ncbi.nlm.nih.gov/pubmed/19363223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809643200
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