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Nucleotide sequence homology requirements of HIV-1-specific short hairpin RNA
The degradation of a selected mRNA species by RNA interference requires a high degree of homology between the short interfering or short hairpin RNA (si or shRNA) and its target. Recent reports have demonstrated that the number and location of nucleotide mismatches affect the activity of si/shRNA. H...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275570/ https://ncbi.nlm.nih.gov/pubmed/14602902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg876 |
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