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Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins
Post-transcriptional inhibition of HIV-1 replication can be achieved by RNA interference (RNAi). The cellular expression of short interfering RNA (siRNA) or short hairpin RNA (shRNA) homologous to regions of the HIV-1 genome decreases viral replication by the selective degradation of targeted RNA. H...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373410/ https://ncbi.nlm.nih.gov/pubmed/14966264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh278 |
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