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Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins

Post-transcriptional inhibition of HIV-1 replication can be achieved by RNA interference (RNAi). The cellular expression of short interfering RNA (siRNA) or short hairpin RNA (shRNA) homologous to regions of the HIV-1 genome decreases viral replication by the selective degradation of targeted RNA. H...

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Detalhes bibliográficos
Main Authors: Boden, Daniel, Pusch, Oliver, Silbermann, Rebecca, Lee, Fred, Tucker, Lynne, Ramratnam, Bharat
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373410/
https://ncbi.nlm.nih.gov/pubmed/14966264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh278
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