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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

A large number of miRNAs have recently been discovered in plants and animals. Development of reverse genetic approaches that act to inhibit microRNA function would facilitate the study of this new class of noncoding RNA. Here we show that 2′-O-methyl oligoribonucleotides, but not 2′-deoxyoligonucleo...

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Detalhes bibliográficos
Main Authors: MEISTER, GUNTER, LANDTHALER, MARKUS, DORSETT, YAIR, TUSCHL, THOMAS
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370948/
https://ncbi.nlm.nih.gov/pubmed/14970398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5235104
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