Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

A large number of miRNAs have recently been discovered in plants and animals. Development of reverse genetic approaches that act to inhibit microRNA function would facilitate the study of this new class of noncoding RNA. Here we show that 2′-O-methyl oligoribonucleotides, but not 2′-deoxyoligonucleo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: MEISTER, GUNTER, LANDTHALER, MARKUS, DORSETT, YAIR, TUSCHL, THOMAS
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Copyright 2004 by RNA Society 2004
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370948/
https://ncbi.nlm.nih.gov/pubmed/14970398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5235104
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