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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

A large number of miRNAs have recently been discovered in plants and animals. Development of reverse genetic approaches that act to inhibit microRNA function would facilitate the study of this new class of noncoding RNA. Here we show that 2′-O-methyl oligoribonucleotides, but not 2′-deoxyoligonucleo...

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Bibliografiske detaljer
Main Authors: MEISTER, GUNTER, LANDTHALER, MARKUS, DORSETT, YAIR, TUSCHL, THOMAS
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2004 by RNA Society 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370948/
https://ncbi.nlm.nih.gov/pubmed/14970398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5235104
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