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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

A large number of miRNAs have recently been discovered in plants and animals. Development of reverse genetic approaches that act to inhibit microRNA function would facilitate the study of this new class of noncoding RNA. Here we show that 2′-O-methyl oligoribonucleotides, but not 2′-deoxyoligonucleo...

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Main Authors: MEISTER, GUNTER, LANDTHALER, MARKUS, DORSETT, YAIR, TUSCHL, THOMAS
格式: Artigo
語言:Inglês
出版: Copyright 2004 by RNA Society 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370948/
https://ncbi.nlm.nih.gov/pubmed/14970398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5235104
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