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Promoter choice affects the potency of HIV-1 specific RNA interference
RNA interference (RNAi) is mediated by small interfering (si) RNAs that target and degrade mRNA in a sequence-specific manner. Cellular expression of siRNA can be achieved by the use of expression cassettes driven by RNA polymerase III (pol III) promoters. Here, we demonstrate that a modified tRNA(m...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212804/ https://ncbi.nlm.nih.gov/pubmed/12930953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg704 |
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