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Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound
Here we report a number of novel JS-K structural analogues with sub-micromolar anti-proliferative activities against human leukemia cell lines HL-60 and U937; JS-K is the anti-cancer lead compound O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate. The ability of t...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755573/ https://ncbi.nlm.nih.gov/pubmed/19364650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.03.115 |
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