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Doublecortin induces mitotic microtubule catastrophe and inhibits glioma cell invasion

Doublecortin (DCX) is a microtubule binding protein that induces growth arrest at the G2-M phase of cell-cycle in glioma and suppresses tumor xenograft in immunocompromised hosts. DCX expression was found in neuronal cells, but lacking in glioma cells. We tested the hypothesis that DCX inhibits glio...

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Bibliografische gegevens
Hoofdauteurs: Santra, Manoranjan, Santra, Sutapa, Roberts, Cindi, Zhang, Rui Lan, Chopp, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755559/
https://ncbi.nlm.nih.gov/pubmed/19094064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05758.x
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