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Regulation of Cre recombinase by ligand-induced complementation of inactive fragments

Cre recombinase is extensively used to engineer the genome of experimental animals. However, its usefulness is still limited by the lack of an efficient temporal control over its activity. To overcome this, we have developed DiCre, a regulatable fragment complementation system for Cre. The enzyme wa...

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Hlavní autoři: Jullien, Nicolas, Sampieri, François, Enjalbert, Alain, Herman, Jean-Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC275488/
https://ncbi.nlm.nih.gov/pubmed/14576331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng131
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