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Regulation of Cre recombinase by ligand-induced complementation of inactive fragments

Cre recombinase is extensively used to engineer the genome of experimental animals. However, its usefulness is still limited by the lack of an efficient temporal control over its activity. To overcome this, we have developed DiCre, a regulatable fragment complementation system for Cre. The enzyme wa...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Jullien, Nicolas, Sampieri, François, Enjalbert, Alain, Herman, Jean-Paul
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275488/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576331/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng131
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