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Regulation of Cre recombinase by ligand-induced complementation of inactive fragments

Cre recombinase is extensively used to engineer the genome of experimental animals. However, its usefulness is still limited by the lack of an efficient temporal control over its activity. To overcome this, we have developed DiCre, a regulatable fragment complementation system for Cre. The enzyme wa...

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Autori principali: Jullien, Nicolas, Sampieri, François, Enjalbert, Alain, Herman, Jean-Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC275488/
https://ncbi.nlm.nih.gov/pubmed/14576331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng131
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