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Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells

While oxidative stress induces mitochondrial DNA (mtDNA) damage, a role for redox in modulating mtDNA oxidation and repair is relatively unexplored. The current study examines the contribution of cellular glutathione (GSH) redox status to menadione (MQ)-induced mtDNA damage and post-oxidant mtDNA re...

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書誌詳細
主要な著者: Circu, Magdalena L., Moyer, Mary P., Harrison, Lynn, Aw, Tak Yee
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754567/
https://ncbi.nlm.nih.gov/pubmed/19647792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.07.032
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