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THE ROLE OF GSH EFFLUX IN STAUROSPORINE-INDUCED APOPTOSIS IN COLONIC EPITHELIAL CELLS
Staurosporine (STP) was shown to induce cell apoptosis through formation of reactive oxygen species, but a role for cellular redox has not been defined. In this study, we report that STP (2μM) caused apoptosis (24±3% at 24h) of human colon adenocarcinoma epithelial cell line HT29 that was preceded b...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610527/ https://ncbi.nlm.nih.gov/pubmed/18840413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.09.011 |
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