CONTRIBUTION OF MITOCHONDRIAL GSH TRANSPORT TO MATRIX GSH STATUS AND COLONIC EPITHELIAL CELL APOPTOSIS

Previously, we showed that cellular glutathione/glutathione disulfide (GSH/GSSG) play an important role in apoptotic signaling, and early studies linked mitochondrial GSH (mtGSH) loss to enhanced cytotoxicity. The current study focuses on the contribution of mitochondrial GSH transport and mitochond...

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Detalhes bibliográficos
Main Authors: Circu, Magdalena L., Rodriguez, Cynthia, Maloney, Ronald, Moyer, Mary Pat, Aw, Tak Yee
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275168/
https://ncbi.nlm.nih.gov/pubmed/18267208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.09.011
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