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Mutations occur in the Ig Sµ region but rarely in Sγ regions prior to class switch recombination
Nucleotide substitutions are found in recombined Ig switch (S) regions and also in unrecombined (germline, GL) Sµ segments in activated splenic B cells. Herein we examine whether mutations are also introduced into the downstream acceptor S regions prior to switch recombination, but find very few mut...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275407/ https://ncbi.nlm.nih.gov/pubmed/14592986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg550 |
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