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Mutations occur in the Ig Sµ region but rarely in Sγ regions prior to class switch recombination

Nucleotide substitutions are found in recombined Ig switch (S) regions and also in unrecombined (germline, GL) Sµ segments in activated splenic B cells. Herein we examine whether mutations are also introduced into the downstream acceptor S regions prior to switch recombination, but find very few mut...

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Détails bibliographiques
Auteurs principaux: Schrader, Carol E., Bradley, Sean P., Vardo, Joycelyn, Mochegova, Sofia N., Flanagan, Erin, Stavnezer, Janet
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC275407/
https://ncbi.nlm.nih.gov/pubmed/14592986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg550
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