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Use of o-phthalaldehyde assay to determine protein contents of Alhydrogel-based vaccines

Aluminum based adjuvants (alum), including aluminum hydroxide (Alhydrogel(®)) and aluminum phosphate are the most commonly used adjuvant in the US. In order to ensure quality of vaccines, regulatory authorities require evaluation of antigen content in final vaccine products. Currently, there are no...

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Detalhes bibliográficos
Main Authors: Zhu, Daming, Saul, Allan, Huang, Shuhui, Martin, Laura B., Miller, Louis H., Rausch, Kelly M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753737/
https://ncbi.nlm.nih.gov/pubmed/19660590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.07.067
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