Phase 1 Trial of AMA1-C1/Alhydrogel plus CPG 7909: An Asexual Blood-Stage Vaccine for Plasmodium falciparum Malaria

BACKGROUND: Apical Membrane Antigen 1 (AMA1), a polymorphic merozoite surface protein, is a leading blood-stage malaria vaccine candidate. This is the first reported use in humans of an investigational vaccine, AMA1-C1/Alhydrogel, with the novel adjuvant CPG 7909. METHODS: A phase 1 trial was conduc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mullen, Gregory E. D., Ellis, Ruth D., Miura, Kazutoyo, Malkin, Elissa, Nolan, Caroline, Hay, Mhorag, Fay, Michael P., Saul, Allan, Zhu, Daming, Rausch, Kelly, Moretz, Samuel, Zhou, Hong, Long, Carole A., Miller, Louis H., Treanor, John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2008
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491586/
https://ncbi.nlm.nih.gov/pubmed/18698359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002940
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