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Phase 1 Study in Malaria Naïve Adults of BSAM2/Alhydrogel®+CPG 7909, a Blood Stage Vaccine against P. falciparum Malaria

A Phase 1 dose escalating study was conducted in malaria naïve adults to assess the safety, reactogenicity, and immunogenicity of the blood stage malaria vaccine BSAM2/Alhydrogel®+ CPG 7909. BSAM2 is a combination of the FVO and 3D7 alleles of recombinant AMA1 and MSP1(42), with equal amounts by wei...

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書誌詳細
主要な著者: Ellis, Ruth D., Wu, Yimin, Martin, Laura B., Shaffer, Donna, Miura, Kazutoyo, Aebig, Joan, Orcutt, Andrew, Rausch, Kelly, Zhu, Daming, Mogensen, Anders, Fay, Michael P., Narum, David L., Long, Carole, Miller, Louis, Durbin, Anna P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464250/
https://ncbi.nlm.nih.gov/pubmed/23056238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046094
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