Phase 1 Study in Malaria Naïve Adults of BSAM2/Alhydrogel®+CPG 7909, a Blood Stage Vaccine against P. falciparum Malaria

A Phase 1 dose escalating study was conducted in malaria naïve adults to assess the safety, reactogenicity, and immunogenicity of the blood stage malaria vaccine BSAM2/Alhydrogel®+ CPG 7909. BSAM2 is a combination of the FVO and 3D7 alleles of recombinant AMA1 and MSP1(42), with equal amounts by wei...

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Detalhes bibliográficos
Main Authors: Ellis, Ruth D., Wu, Yimin, Martin, Laura B., Shaffer, Donna, Miura, Kazutoyo, Aebig, Joan, Orcutt, Andrew, Rausch, Kelly, Zhu, Daming, Mogensen, Anders, Fay, Michael P., Narum, David L., Long, Carole, Miller, Louis, Durbin, Anna P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464250/
https://ncbi.nlm.nih.gov/pubmed/23056238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046094
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