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Anthrax Sub-unit Vaccine: the structural consequences of binding rPA83 to Alhydrogel(®)

An anthrax sub-unit vaccine, comprising recombinant Protective Antigen (rPA83) and aluminium hydroxide adjuvant (Alhydrogel(®)) is currently being developed. Here a series of biophysical techniques have been applied to free and adjuvant bound antigen. Limited proteolysis and fluorescence identified...

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Hlavní autoři: Soliakov, Andrei, Kelly, Ian. F., Lakey, Jeremy H, Watkinson, Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244517/
https://ncbi.nlm.nih.gov/pubmed/21964315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2011.09.009
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