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The DNA-PK Catalytic Subunit Regulates Bax-mediated Excitotoxic Cell Death by Ku70 Phosphorylation

DNA repair deficiency results in neurodegenerative disease and increased susceptibility to excitotoxic cell death, suggesting a critical, but undefined role for DNA damage in neurodegeneration. We compared DNA damage, Ku70-Bax interaction, and Bax-dependent excitotoxic cell death in kainic acid-trea...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Jia, Naegele, Janice R., Lin, Stanley L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753734/
https://ncbi.nlm.nih.gov/pubmed/19664609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.07.101
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