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The DNA-PK Catalytic Subunit Regulates Bax-mediated Excitotoxic Cell Death by Ku70 Phosphorylation
DNA repair deficiency results in neurodegenerative disease and increased susceptibility to excitotoxic cell death, suggesting a critical, but undefined role for DNA damage in neurodegeneration. We compared DNA damage, Ku70-Bax interaction, and Bax-dependent excitotoxic cell death in kainic acid-trea...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753734/ https://ncbi.nlm.nih.gov/pubmed/19664609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.07.101 |
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