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Suppression of murine SLE by oral anti-CD3: inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells

Lupus is an antibody-mediated autoimmune disease. The production of pathogenic, class switched and affinity maturated autoantibodies in lupus is dependent on T cell help. A potential mechanism of disease pathogenesis is a lack of control of pathogenic T helper cells by regulatory T cells in lupus. I...

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Main Authors: Wu, HY, Center, EM, Tsokos, GC, Weiner, HL
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753460/
https://ncbi.nlm.nih.gov/pubmed/19433458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203308100511
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