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Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4(+)CD25(-)LAP(+) Regulatory T Cell and Is Associated with Down-Regulation of IL-17(+)CD4(+)ICOS(+)CXCR5(+) Follicular Helper T Cells
Lupus is an Ab-mediated autoimmune disease. One of the potential contributors to the development of systemic lupus erythematosus is a defect in naturally occurring CD4(+)CD25(+) regulatory T cells. Thus, the generation of inducible regulatory T cells that can control autoantibody responses is a pote...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753458/ https://ncbi.nlm.nih.gov/pubmed/18941193 |
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