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Expansion of CD4(+)CD25(+ )helper T cells without regulatory function in smoking and COPD
BACKGROUND: Regulatory T cells have been implicated in the pathogenesis of COPD by the increased expression of CD25 on helper T cells along with enhanced intracellular expression of FoxP3 and low/absent CD127 expression on the cell surface. METHOD: Regulatory T cells were investigated in BALF from n...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127771/ https://ncbi.nlm.nih.gov/pubmed/21651772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-74 |
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