Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

Chromatin modifications are an important component of the of DNA damage response (DDR) network that safeguard genomic integrity. Recently, we demonstrated nucleotide excision repair (NER)–dependent histone H2A ubiquitination at sites of ultraviolet (UV)-induced DNA damage. In this study, we show a s...

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Autors principals: Marteijn, Jurgen A., Bekker-Jensen, Simon, Mailand, Niels, Lans, Hannes, Schwertman, Petra, Gourdin, Audrey M., Dantuma, Nico P., Lukas, Jiri, Vermeulen, Wim
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753161/
https://ncbi.nlm.nih.gov/pubmed/19797077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902150
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