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Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

Chromatin modifications are an important component of the of DNA damage response (DDR) network that safeguard genomic integrity. Recently, we demonstrated nucleotide excision repair (NER)–dependent histone H2A ubiquitination at sites of ultraviolet (UV)-induced DNA damage. In this study, we show a s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marteijn, Jurgen A., Bekker-Jensen, Simon, Mailand, Niels, Lans, Hannes, Schwertman, Petra, Gourdin, Audrey M., Dantuma, Nico P., Lukas, Jiri, Vermeulen, Wim
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753161/
https://ncbi.nlm.nih.gov/pubmed/19797077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902150
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