Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

Chromatin modifications are an important component of the of DNA damage response (DDR) network that safeguard genomic integrity. Recently, we demonstrated nucleotide excision repair (NER)–dependent histone H2A ubiquitination at sites of ultraviolet (UV)-induced DNA damage. In this study, we show a s...

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Detalhes bibliográficos
Main Authors: Marteijn, Jurgen A., Bekker-Jensen, Simon, Mailand, Niels, Lans, Hannes, Schwertman, Petra, Gourdin, Audrey M., Dantuma, Nico P., Lukas, Jiri, Vermeulen, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753161/
https://ncbi.nlm.nih.gov/pubmed/19797077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902150
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