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Vaccinia Virus K1L and C7L Inhibit Antiviral Activities Induced by Type I Interferons

Cellular tropism of vaccinia virus (VACV) is regulated by host range genes, including K1L, C7L, and E3L. While E3L is known to support viral replication by antagonizing interferon (IFN) effectors, including PKR, the exact functions of K1L and C7L are unclear. Here, we show that K1L and C7L can also...

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Detalhes bibliográficos
Main Authors: Meng, Xiangzhi, Jiang, Canhua, Arsenio, Janilyn, Dick, Kevin, Cao, Jingxin, Xiang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753149/
https://ncbi.nlm.nih.gov/pubmed/19656868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01260-09
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