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Vaccinia Virus E3 Suppresses Expression of Diverse Cytokines through Inhibition of the PKR, NF-κB, and IRF3 Pathways

The vaccinia virus double-stranded RNA binding protein E3 has been demonstrated to inhibit the expression of cytokines, including beta interferon (IFN-β) and tumor necrosis factor alpha (TNF-α). However, few details regarding the molecular mechanisms of this inhibition have been described. Using rea...

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Detalhes bibliográficos
Main Authors: Myskiw, Chad, Arsenio, Janilyn, van Bruggen, Rebekah, Deschambault, Yvon, Cao, Jingxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698532/
https://ncbi.nlm.nih.gov/pubmed/19369349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02570-08
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