Mutational Analysis of Vaccinia Virus E3 Protein: the Biological Functions Do Not Correlate with Its Biochemical Capacity To Bind Double-Stranded RNA

Vaccinia E3 protein has the biochemical capacity of binding to double-stranded RNA (dsRNA). The best characterized biological functions of the E3 protein include its host range function, suppression of cytokine expression, and inhibition of interferon (IFN)-induced antiviral activity. Currently, the...

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Vydáno v:J Virol
Hlavní autoři: Dueck, Kevin J., Hu, YuanShen (Sandy), Chen, Peter, Deschambault, Yvon, Lee, Jocelyn, Varga, Jessie, Cao, Jingxin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442530/
https://ncbi.nlm.nih.gov/pubmed/25740987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03288-14
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