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Trifluoperazine: a ryanodine receptor agonist

Trifluoperazine (TFP), a phenothiazine, is a commonly used antipsychotic drug whose therapeutic effects are attributed to its central anti-adrenergic and antidopaminergic actions. However, TFP is also a calmodulin (CaM) antagonist and alters the Ca binding properties of calsequestrin (CSQ). The CaM...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Qin, Jia, Zima, Aleksey V., Porta, Maura, Blatter, Lothar A., Fill, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752966/
https://ncbi.nlm.nih.gov/pubmed/19277699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-009-0658-y
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