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CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53
p300 and CREB-binding protein (CBP) act as multifunctional regulators of p53 via acetylase and polyubiquitin ligase (E4) activities. Prior work in vitro has shown that the N-terminal 595 aa of p300 encode both generic ubiquitin ligase (E3) and p53-directed E4 functions. Analysis of p300 or CBP-defic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752525/ https://ncbi.nlm.nih.gov/pubmed/19805293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904305106 |
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