CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53

p300 and CREB-binding protein (CBP) act as multifunctional regulators of p53 via acetylase and polyubiquitin ligase (E4) activities. Prior work in vitro has shown that the N-terminal 595 aa of p300 encode both generic ubiquitin ligase (E3) and p53-directed E4 functions. Analysis of p300 or CBP-defic...

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Detaylı Bibliyografya
Asıl Yazarlar: Shi, Dingding, Pop, Marius S., Kulikov, Roman, Love, Ian M., Kung, Andrew L., Grossman, Steven R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752525/
https://ncbi.nlm.nih.gov/pubmed/19805293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904305106
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