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It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53
The transcription factor p53 regulates numerous cellular processes to guard against tumorigenesis. Cell-cycle inhibition, apoptosis, and autophagy are all regulated by p53 in a cell- and context-specific manner, underscoring the need for p53 activity to be kept low in most circumstances. p53 is kept...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publications
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494362/ https://ncbi.nlm.nih.gov/pubmed/23150758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912455198 |
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