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SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis
Resistance to anoikis, the subtype of apoptosis triggered by lack of adhesion, contributes to malignant transformation and the development of metastasis. Although several lines of evidence suggest that p53 plays a critical role in anoikis, the pathway(s) that connect cell detachment to p53 remain un...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752275/ https://ncbi.nlm.nih.gov/pubmed/19622832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000369 |
| Etiketak: |
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