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NF-κB2 (p100) limits TNF-α–induced osteoclastogenesis
Bone undergoes a continuous cycle of renewal, and osteoclasts — the cells responsible for bone resorption — play a pivotal role in bone homeostasis. This resorption is largely mediated by inflammatory cytokines such as TNF-α. In this issue of the JCI, Yao et al. demonstrate that the NF-κB precursor...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752088/ https://ncbi.nlm.nih.gov/pubmed/19770519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40629 |
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