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NF-κB2 (p100) limits TNF-α–induced osteoclastogenesis

Bone undergoes a continuous cycle of renewal, and osteoclasts — the cells responsible for bone resorption — play a pivotal role in bone homeostasis. This resorption is largely mediated by inflammatory cytokines such as TNF-α. In this issue of the JCI, Yao et al. demonstrate that the NF-κB precursor...

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Detalhes bibliográficos
Main Authors: Tanaka, Sakae, Nakano, Hiroyasu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752088/
https://ncbi.nlm.nih.gov/pubmed/19770519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40629
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