TNF-α and RANKL promote osteoclastogenesis by upregulating RANK via the NF-κB pathway

Although tumor necrosis factor alpha (TNF-α) is known to serve a critical role in the pathogenesis of inflammatory osteolysis, the exact mechanisms underlying the effects of TNF-α on osteoclast recruitment and differentiation remain unclear. To investigate the mechanisms by which TNF-α influences os...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Luo, Gang, Li, Fangfei, Li, Xiaoming, Wang, Zheng-Guo, Zhang, Bo
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928634/
https://ncbi.nlm.nih.gov/pubmed/29512766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8698
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