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SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production
Various acute and chronic inflammatory stimuli increase the number and activity of pulmonary mucus-producing goblet cells, and goblet cell hyperplasia and excess mucus production are central to the pathogenesis of chronic pulmonary diseases. However, little is known about the transcriptional program...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752084/ https://ncbi.nlm.nih.gov/pubmed/19759516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39731 |
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