A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans

Seborrheic keratoses (SKs) are common, benign epithelial tumors of the skin that do not, or very rarely, progress into malignancy, for reasons that are not understood. We investigated this by gene expression profiling of human SKs and cutaneous squamous cell carcinomas (SCCs) and found that several...

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Detalhes bibliográficos
Main Authors: Mandinova, Anna, Kolev, Vihren, Neel, Victor, Hu, Bing, Stonely, Wesley, Lieb, Jocelyn, Wu, Xunwei, Colli, Claudia, Han, Rong, Pazin, Mike, Ostano, Paola, Dummer, Reinhard, Brissette, Janice L., Dotto, G. Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752067/
https://ncbi.nlm.nih.gov/pubmed/19729838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38543
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