Laddar...
Pharmacokinetic Interaction between the Flavonoid Luteolin and γ-Hydroxybutyrate in Rats: Potential Involvement of Monocarboxylate Transporters
Monocarboxylate transporter 1 (MCT1) has been previously reported as an important determinant of the renal reabsorption of the drug of abuse, γ-hydroxybutyrate (GHB). Luteolin is a potent MCT1 inhibitor, inhibiting the uptake of GHB with an IC(50) of 0.41 μM in MCT1-transfected MDA-MB231 cells. The...
Sparad:
| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Springer US
2008
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751446/ https://ncbi.nlm.nih.gov/pubmed/18446505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-007-9001-8 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|