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A novel monocarboxylate transporter inhibitor as a potential treatment strategy for γ-hydroxybutyric acid overdose

PURPOSE: Monocarboxylate transporter (MCT) inhibition represents a potential treatment strategy for γ-hydroxybutyric acid (GHB) overdose by blocking its renal reabsorption in the kidney. This study further evaluated the effects of a novel, highly potent MCT inhibitor, AR-C155858, on GHB toxicokineti...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Vijay, Nisha, Morse, Bridget L., Morris, Marilyn E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425608/
https://ncbi.nlm.nih.gov/pubmed/25480120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1583-0
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