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SOCS1 Downregulation in Dendritic Cells Promotes Memory T Cell Responses

SOCS1-1 is crucial for control of immune cell cytokine expression, including those cytokines known to enable memory T cell formation and homeostasis. In this study, we found that immunization with SOCS1-downregulated bone marrow-derived dendritic cells generated increased antigen-specific CD8(+) T m...

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Autors principals: Aldrich, Melissa, Sanders, Denise, Lapteva, Natasha, Chen, Si-Yi
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750824/
https://ncbi.nlm.nih.gov/pubmed/18222020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.11.020
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