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Targeting the Intratumoral Dendritic Cells by the Oncolytic Adenoviral Vaccine Expressing RANTES Elicits Potent Antitumor Immunity

Dendritic cells (DCs) are professional antigen (Ag)-presenting cells capable of inducing immune responses to tumor Ags and, therefore, play a central role in the induction of antitumor immunity. There is a large amount of evidence, however, about paucity of tumor-associated DCs and that DCs’ immunog...

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Autores principales: Lapteva, Natalia, Aldrich, Melissa, Weksberg, David, Rollins, Lisa, Goltsova, Tatiana, Chen, Si-Yi, Huang, Xue F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146345/
https://ncbi.nlm.nih.gov/pubmed/19238013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318193d31e
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