Foxo1 Links Hyperglycemia to LDL Oxidation and Endothelial Nitric Oxide Synthase Dysfunction in Vascular Endothelial Cells

OBJECTIVE: Atherosclerotic cardiovascular disease is the leading cause of death among people with diabetes. Generation of oxidized LDLs and reduced nitric oxide (NO) availability because of endothelial NO synthase (eNOS) dysfunction are critical events in atherosclerotic plaque formation. Biochemica...

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Bibliographische Detailangaben
Hauptverfasser: Tanaka, Jun, Qiang, Li, Banks, Alexander S., Welch, Carrie L., Matsumoto, Michihiro, Kitamura, Tadahiro, Ido-Kitamura, Yukari, DePinho, Ronald A., Accili, Domenico
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750207/
https://ncbi.nlm.nih.gov/pubmed/19584310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0167
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