A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

Forkhead box O (Foxo) transcription factors govern metabolism and cellular differentiation. Unlike Foxo-dependent metabolic pathways and target genes, the mechanisms by which these proteins regulate differentiation have not been explored. Activation of Notch signaling mimics the effects of Foxo gain...

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Main Authors: Kitamura, Tadahiro, Kitamura, Yukari Ido, Funahashi, Yasuhiro, Shawber, Carrie J., Castrillon, Diego H., Kollipara, Ramya, DePinho, Ronald A., Kitajewski, Jan, Accili, Domenico
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950461/
https://ncbi.nlm.nih.gov/pubmed/17717603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32054
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