Dengue Virus Infection and Virus-Specific HLA-A2 Restricted Immune Responses in Humanized NOD-scid IL2rγ(null) Mice

BACKGROUND: The lack of a suitable animal model to study viral and immunological mechanisms of human dengue disease has been a deterrent to dengue research. METHODOLOGY/PRINCIPAL FINDINGS: We sought to establish an animal model for dengue virus (DENV) infection and immunity using non-obese diabetic/...

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Autori principali: Jaiswal, Smita, Pearson, Todd, Friberg, Heather, Shultz, Leonard D., Greiner, Dale L., Rothman, Alan L., Mathew, Anuja
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749937/
https://ncbi.nlm.nih.gov/pubmed/19802382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007251
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