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NOD-scidIl2rg(tm1Wjl) and NOD-Rag1(null)Il2rg(tm1Wjl): A Model for Stromal Cell–Tumor Cell Interaction for Human Colon Cancer

BACKGROUND/AIMS: Stromal cells and the extracellular environment are vital to human tumors, influencing growth and response to therapy. Human tumor cell lines lack stroma and transplantation into immunodeficient mice does not allow meaningful analyses of the effects of stroma on tumor cell growth. S...

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Detalhes bibliográficos
Main Authors: Maykel, Justin, Liu, Jian Hua, Li, Hanchen, Shultz, Leonard D., Greiner, Dale L., Houghton, JeanMarie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032472/
https://ncbi.nlm.nih.gov/pubmed/24798995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-014-3168-5
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